19 x 9.5 +12 will just give you more lip and a tad more concave on the spokes, which will give a more aggressive look on you wheels.
19 x 10.5 +22 will give you better rear traction due to it being a inch wider of tyre but a less aggressive offset.
R33 GTR's have wide rear guards, preferably you run 19 x 10.5 +12 as the stock R33 GTR wheels are 17 x 9 +30 and the look tiny.
But if you got 19 x 10.5 +22, it should still look ok but won't fill out the guards as good as 19 x 10.5 +12.
19 x 9.5 +12
19 x 10.5 +12 fills out the guards nicely.
Don't bother running spacers and get the correct offset to fill out the guards.