The oil that is pumped into the rocker covers (among other areas) to lubricate the camshafts, flows back to the sump under gravity through various passageways in the block.
If oil can flow down these passageways, oil vapours can flow up the same passageways from the sump.
I can't see any reason to block off the PCV valve - the catch can is simply a place where the oil vapours can condense, leaving "clean" air to proceed to the PCV valve.
In my own setup, I only have the catch can on the induction side so I don't ingest vapours back through the turbo side. Since the PCV only operates under low vacuum / low load situations, I'm not concerned about ingesting a few vapours in a situation where detonation isn't going to be a problem.